Update installation instructions

README.md

@@ -24,10 +24,20 @@ The [public postgres database](https://rnacentral.org/help/public-database) is c
 If you want to use another database, add the following environment variables: `DB_HOST`, `DB_NAME`, `DB_USER`, 
 `DB_PASSWORD`, and `DB_PORT`.
 
-3. Run the app using [Docker](https://www.docker.com):
+3. For Mac OS users, install [mutagen](https://mutagen.io/) (Docker on Mac has some performance issues)
 
   ```
+  brew install mutagen-io/mutagen/mutagen-beta
+  ```    
+ 
+4. Run the app using [Docker](https://www.docker.com):
+
+  ```
+  For Linux users:  
   docker-compose -f docker-compose.local.yml up --build
+
+  For Mac OS users:
+  mutagen compose -f docker-compose.local.mac.yml up --build
   ```
 
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