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petsalakilab
2D_CRISPR_LibraryGeneSelection
Commits
914d173d
Commit
914d173d
authored
Dec 08, 2021
by
Sayed Rzgar Hosseini
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Update Script08.R
parent
cab2f7d3
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Scripts/Script08.R
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914d173d
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@@ -54,7 +54,7 @@ DC_UP<-as.character(ANOVA_COLO$DRUG_NAME.x[INDX_C_UP]) # Drug names of the expre
DC_MUT
<-
as.character
(
ANOVA_COLO
$
DRUG_NAME.x
[
INDX_C_MUT
])
# Drug names of the Mutation based biomarkers
#######################################################################################################################################################
# Criteri
a
1: An anchor gene is a biomarker of resistance to a drug that targets the candidate gene
# Criteri
on
1: An anchor gene is a biomarker of resistance to a drug that targets the candidate gene
# Expression based [Breast]
New_Candidates_Breast
<-
c
()
intersect
(
anchor_breast
,
B_up
)
# only: "PARP1"
...
...
@@ -104,7 +104,7 @@ for (i in 1:length(setDC)){
#######################################################################################################################################################
#######################################################################################################################################################
# Criteri
a
2: One of the anchor genes must be the target of a drug that targets the candidate gene
# Criteri
on
2: One of the anchor genes must be the target of a drug that targets the candidate gene
# Drug names of the expression based biomarkers [Breast]
for
(
i
in
1
:
length
(
DB_UP
)){
sel
<-
which
(
as.character
(
ANOVA_BREAST
$
DRUG_NAME.x
)
==
DB_UP
[
i
])
#Retrieve the rows with the given drug name
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