Change-log.md

@@ -2,6 +2,13 @@
 
 Please note all dates are expressed as [ISO-8601](http://en.wikipedia.org/wiki/ISO_8601).
 
+# 4.5 - 2016/03/09
+
+* New Regulation endpoint `[/ld/:species/region/]` to compute LD values between all pairs of variants in a defined region
+* New variation endpoint `[/transcript_haplotypes]` to compute observed transcript haplotype sequences based on phased genotype data
+* `[/info/external_dbs/]` now allows restricting the list of external database entries to a specified species
+* GA4GH endpoints updated to version 0.6.0
+
 # 4.4 - 2015/12/08
 
 ## New features