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ChEMBL
EUbOPEN
EUbOPEN Web
Commits
66f2e92a
Commit
66f2e92a
authored
3 years ago
by
David Mendez
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Add mockup of cellular assay and target engagement section
parent
daf14207
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1 merge request
!5
Add compounds and target browser mockups
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2 changed files
components/report_cards/chemical_probe/ProbeProfile.vue
+0
-11
0 additions, 11 deletions
components/report_cards/chemical_probe/ProbeProfile.vue
report_cards_structure/CompoundReportCardGenerator.js
+9
-2
9 additions, 2 deletions
report_cards_structure/CompoundReportCardGenerator.js
with
9 additions
and
13 deletions
components/report_cards/chemical_probe/ProbeProfile.vue
+
0
−
11
View file @
66f2e92a
<
template
>
<v-card>
<v-card-title>
In vitro Potency
&
Selectivity
</v-card-title>
<v-card-text>
<p
class=
"text-justify"
>
PFI-6 shows potent activity on MLLT1/3. PFI-6 is universally inactive in
...
...
@@ -52,16 +51,6 @@
</tbody>
</v-simple-table>
</v-card-text>
<v-card-title>
Cellular Assay and Target Engagement:
</v-card-title>
<v-card-text>
<p
class=
"text-justify"
>
In a NanoBRET cellular target engagement assay, PFI-6 displays potent
binding, with an average IC50 value of 0.76 μM (±0.1). In comparison,
PFI-6N shows no binding properties (up to 30 μM). Further in cell
validation using a Fluorescence Recovery After Photobleaching (FRAP)
assay has been used to confirm target inhibition by PFI-6.
</p>
</v-card-text>
</v-card>
</
template
>
...
...
This diff is collapsed.
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report_cards_structure/CompoundReportCardGenerator.js
+
9
−
2
View file @
66f2e92a
import
Summary
from
'
~/components/report_cards/chemical_probe/Summary.vue
'
import
ControlStructuresAndUse
from
'
~/components/report_cards/chemical_probe/ControlStructuresAndUse.vue
'
import
CellularAssayTargetEngagement
from
'
~/components/report_cards/chemical_probe/CellularAssayTargetEngagement.vue
'
import
ProbeProfile
from
'
~/components/report_cards/chemical_probe/ProbeProfile.vue
'
import
CrystalStructures
from
'
~/components/report_cards/chemical_probe/CrystalStructures.vue
'
...
...
@@ -20,17 +21,23 @@ const methods = {
component
:
ControlStructuresAndUse
,
index
:
1
,
},
{
id
:
'
CellularAssayTargetEngagement
'
,
title
:
'
Cellular Assay and Target Engagement
'
,
component
:
CellularAssayTargetEngagement
,
index
:
2
,
},
{
id
:
'
ProbeProfile
'
,
title
:
'
Probe Profile
'
,
component
:
ProbeProfile
,
index
:
2
,
index
:
3
,
},
{
id
:
'
CrystalStructures
'
,
title
:
'
Crystal Structures
'
,
component
:
CrystalStructures
,
index
:
3
,
index
:
4
,
},
],
}
...
...
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